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Anti-Vascular Endothelial Growth Factor Injection-to-Surgery Interval in Diabetic Vitrectomy: A Systematic Review and Meta-Analysis

This Elsevier-published journal article is a systematic review and meta-analysis examining the timing between anti-vascular endothelial growth factor injections and vitrectomy in patients with diabetic eye disease. The supplied source metadata includes title, publisher, and publication date but provides no study findings or details.

Figure 3. Pro-tumour functions of γδ T cells and the negative regulation of their anti-tumour capacity. Pro-tumour functions of γδ T cells include direct immune suppressor functions blocking αβ T-cell cytotoxicity and DC maturation, promoting angiogenesis and stimulating immune-suppressive neutrophil expansion. γδ T cells can recruit/promote suppressive polymorphonuclear cells (PMNs), facilitated by IL-17, IL-23 and IL-1β feedback loops. Negative regulation of γδ T-cell anti-tumour activity can
Illustrative image: Figure 3. Pro-tumour functions of γδ T cells and the negative regulation of their anti-tumour capacity. Pro-tumour functions of γδ T cells include direct immune suppressor functions blocking αβ T-cell cytotoxicity and DC maturation, promoting angiogenesis and stimulating immune-suppressive neutrophil expansion. γδ T cells can recruit/promote suppressive polymorphonuclear cells (PMNs), facilitated by IL-17, IL-23 and IL-1β feedback loops. Negative regulation of γδ T-cell anti-tumour activity can — Schönefeldt, S.; Wais, T.; Herling, M.; Mustjoki, S.; Bekiaris, V.; Moriggl, R.; Neubauer, H.A./Wikimedia Commons, CC BY 4.0

Categories: public-health

Generated scores

Scores are based on the cited reporting and use a 1–10 scale. Read the methodology.

Confidence
5/10
Geographic reach
2/10
Global importance
3/10
Impact magnitude
3/10
Positivity
5/10
Urgency
2/10

Why it matters

Evidence on the optimal injection-to-surgery interval could inform clinical decisions for diabetic vitrectomy timing.

Sources

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