Planet Briefing

First published · Last updated

P30-2 Structurally rare EML4-ALK identified by next generation sequencing in a NSCLC patient with bilateral ovarian metastases

Journal article reporting identification of a structurally rare EML4-ALK by next-generation sequencing in a non-small cell lung cancer (NSCLC) patient with bilateral ovarian metastases. Publisher metadata notes Elsevier BV and classifies the content as a journal article.

Scaffolds are constructed by linking contigs using information from paired end reads, during this process a number of unknown bases are usually found between the sequences of the linked contigs. To use the information obtained by scaffolding, Scaftigs can be constructed by extracting the contiguous sequences that lack unknown bases (Ns). a) Contig Length Distribution. Histograms of the contig lengths illustrate the number of contigs within a certain size fraction for assemblies of Illumina conti
Illustrative image: Scaffolds are constructed by linking contigs using information from paired end reads, during this process a number of unknown bases are usually found between the sequences of the linked contigs. To use the information obtained by scaffolding, Scaftigs can be constructed by extracting the contiguous sequences that lack unknown bases (Ns). a) Contig Length Distribution. Histograms of the contig lengths illustrate the number of contigs within a certain size fraction for assemblies of Illumina conti — Mende D, Waller A, Sunagawa S, Järvelin A, Chan M, Arumugam M, Raes J, Bork P/Wikimedia Commons, CC BY 3.0

Categories: science-and-space, public-health

Generated scores

Scores are based on the cited reporting and use a 1–10 scale. Read the methodology.

Confidence
4/10
Geographic reach
2/10
Global importance
3/10
Impact magnitude
3/10
Positivity
2/10
Urgency
2/10

Why it matters

The report documents a rare molecular alteration in a cancer patient that is of interest to oncology research.

Sources

Report an issue