Planet Briefing

First published · Last updated

PT2.11.03 Phase I Study of Trametinib, Anlotinib, and Tislelizumab in KRAS-Mutant NSCLC: Safety, RP2D, and Preliminary Efficacy

Journal article reports a Phase I clinical study testing trametinib, anlotinib, and tislelizumab in KRAS‑mutant non‑small cell lung cancer, focusing on safety, recommended phase 2 dose (RP2D), and preliminary efficacy. Publisher listed as Elsevier BV; no further trial details are provided in the supplied fields.

Categories: science-and-space, public-health

Generated scores

Scores are based on the cited reporting and use a 1–10 scale. Read the methodology.

Confidence
6/10
Geographic reach
1/10
Global importance
2/10
Impact magnitude
3/10
Positivity
5/10
Urgency
2/10

Why it matters

The study evaluates safety and dosing for a combination therapy in KRAS‑mutant NSCLC.

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