First published · Last updated
PT2.11.03 Phase I Study of Trametinib, Anlotinib, and Tislelizumab in KRAS-Mutant NSCLC: Safety, RP2D, and Preliminary Efficacy
Journal article reports a Phase I clinical study testing trametinib, anlotinib, and tislelizumab in KRAS‑mutant non‑small cell lung cancer, focusing on safety, recommended phase 2 dose (RP2D), and preliminary efficacy. Publisher listed as Elsevier BV; no further trial details are provided in the supplied fields.
Categories: science-and-space, public-health
Generated scores
Scores are based on the cited reporting and use a 1–10 scale. Read the methodology.
- Confidence
- 6/10
- Geographic reach
- 1/10
- Global importance
- 2/10
- Impact magnitude
- 3/10
- Positivity
- 5/10
- Urgency
- 2/10
Why it matters
The study evaluates safety and dosing for a combination therapy in KRAS‑mutant NSCLC.

