First published 10/3/2026, 8:43:15 PM · Last updated 10/3/2026, 8:43:15 PM

Renal Insufficiency in Patients Treated with High Dose Methotrexate

A 1988 journal article from MJS Publishing reports kidney dysfunction observed among patients receiving high-dose methotrexate. The supplied excerpt includes only publisher and content type and provides no study details or outcomes.

Illustrative image: Ultrasound of left kidney renal parenchymal disease. The cortex of the kidney should have been less echogenic when compared to a normal renal cortex. The kidney size is 9.9 cm. The parenchymal thickness is 1.5 cm. — Cerevisae/Wikimedia Commons, CC BY-SA 4.0

Categories: public-health, science-and-space

Generated scores

Scores are based on the cited reporting and use a 1–10 scale. Read the methodology.

Confidence: 2/10How certain the assessment is based on the clarity and evidence in the cited reporting.
Geographic reach: 1/10How widely the event reaches, from a local area (1) to worldwide impact (10).
Global importance: 3/10The event's broader significance, from limited importance (1) to major global importance (10).
Impact magnitude: 3/10The scale or severity of the real-world impact, from minor (1) to extreme (10).
Positivity: 2/10How harmful or beneficial the event is, from strongly harmful (1) to strongly positive (10).
Urgency: 2/10How time-sensitive the event is, from low urgency (1) to immediate attention needed (10).

Why it matters

Information is relevant to patient safety and clinicians prescribing high-dose methotrexate.

Sources

Renal Insufficiency in Patients Treated with High Dose MethotrexateMetadata provided by Crossref. Usage terms

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